Sunday, May 2, 2010

Non-small Cell Lung Cancer (NSCLC)

Non-small Cell Lung Cancer counts 75% of all lung cancer. Unlike small cell lung cancer, it grouped altogether because their prognosis and management are similar. There are three subtypes of non-small cell lung cancer adenocarcinoma, squamous cell carcinoma, and large cell lung cancer.

Adenocarcinoma is the most common of non-small cell lung cancer and counting 40% of all. Adenocarcinoma was previously known as the most common type of lung cancer in women and non-smokers, however, the incidence of adenocarcinoma has increased in the last two decades and it is now the most common histological subtype in both males and females. The reason for the increasing incidence of adenocarcinoma is not well understood, but may be related to changing patterns of smoking. Adenocarcinomas tend to be peripherally located, smaller and vary histological from well-differentiated tumours to solid masses with occasional mucin-producing glands and cells.


A subtype of adenocarcinoma, the bronchioloalveolar carcinoma, is more common in female never-smokers, and may have different responses to treatment. Bronchioloalveolar carcinoma is a very rare type of lung cancer.

Accounting for 25% of lung cancers, squamous cell lung carcinoma usually starts near a central bronchus. A hollow cavity and associated necrosis are commonly found at the center of the tumor. Well-differentiated squamous cell lung cancers often grow more slowly than other cancer types.

Main Article: Lung Cancer Types

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